We have developed an integrated ion liquid chromatography chip, which is integrated with column, frits/filters, injector and conductivity detector. On-chip separation and detection of anions in water (~25ppm) have been successfully demonstrated. The detection limit is estimated to be 1ppm for the common anions. A much-improved 2nd-genaration chip is currently being developed to do better injection, separation, and detection. A palm-sized wireless LC system based on the LC chip is also actively being developed.