Lab-on-Chip aquatic microorganism analysis system is a new initiative that aims to expedite research in marine biology using chip-based technology. The miniaturized device reduces the total sample and detection time. Also, the chips can be fabricated in large quantities with minimal cost so many experiments can be run in parallel. Our project is organized into two main research areas. First, we would like to develop a chip to monitor the content of the sea water and assess the concentration of different algae. The chip will take in sea water sample, separate the cells based on size, and a downstream impedance sensor will count the number of cells. The second main area of this project is to make a chip that can culture algae and screen for factors inducing toxin production. The exact causes for Peudo-nitzschia to produce toxins are unclear, and we would like to make a chip that cultures Pseudo-nitzschia under different growing conditions.